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It also plays an important role in preventing cardiovascular disease by regulating levels of harmful amino acids and proteins

NO promotes mitochondrial biogenesis primarily by activating key transcriptional regulators, including peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1), nuclear respiratory factor (Nrf-1), nuclear factor erythroid 2 -related factor 2 (Nrf-2), and mitochondrial transcription factor A (TFAM)

How to use: Mix a few drops of fresh lemon juice with one teaspoon of honey

A limitation of the study is the necessity for in vitro and further in vivo studies to investigate additional protective mechanistic pathways of MCP against MTX-induced hepatic and pulmonary toxicity